Testes multiply mutations

The testes in humans may act as mutation multipliers that raise the odds of passing improved DNA to offspring – but that can also backfire by increasing the frequency of certain diseases.

...The data did not support the theory that the site of the mutation in the Apert gene is unusually prone to DNA change.

In my opinion, it's not the site that receives more damage, but rather those cells "choose" not to repair themselves, because they know that when they create sperm, that sperm will have an effect on the next generation, and mutations are good for the species.

I would further argue that the DNA selectively repairs itself based on what it thinks are good mutations and bad mutations. Obviously it gets it wrong a lot of the time, but it could be the mechanism that has made us the amazing creatures we are today.